Happy anniversary, Doubleday. This is my thirtieth review for you.

Big thanks go to Net Galley and Doubleday for the review copy.

I wanted to read Kolker’s book because so little is written about schizophrenia for the general readership. My best friend’s older brother was schizophrenic, and sometimes she would phone me crying and whispering from the floor of her bedroom closet. The bro—let’s call him Marco–was a large person, over six feet tall with a towering red afro that made him appear even larger. He and my friend were both adopted, and their parents weren’t nearly that big. Marco hated taking his medication, and once he reached his teens, he self-medicated with every street drug he could get his hands on. As a result, he often became violent, breaking out all of the windows of the family home and assaulting his poor sweet mother with a crowbar before the cops arrived to haul him off to the hospital again.

And so I wondered, when I saw this book, whether this was a common experience (yes,) and what inroads had been made in the decades between then and now (very few.)

The Galvin family is an anomaly, a very large family of twelve children, half of whom were stricken and the other half traumatized from growing up with them. The family participated in The Human Genome Project, a compilation of genetic samples and other information aimed at unlocking Mother Nature’s terrible secrets. Of course, researchers were also absorbed in the question of nature versus nurture.

Kolker does an outstanding job of chronicling the Galvin family’s history alternately with passages about what was known about this disease at the time when the eldest sibling began to show symptoms, and what has been learned since. It’s a lot of information to organize and share, and who knows what information he weeded out as unnecessary, because one has to stop somewhere.

When the Galvin children were diagnosed in the mid-twentieth century, professionals in the field leaned heavily toward the idea that there was no hereditary cause for the condition, but instead embraced a “mother-as-monster” theory. Because of this, Mimi Galvin, the mother of all of those children, was inclined to stonewall rather than seek help. But who could blame her? Our society was only slightly removed from the days when the ‘crazy’ family member was locked in the attic. (“That thumping sound? Oh dear heaven, perhaps that old raccoon has snuck back in. Enjoy your pie; we’ll chase him out of there after you’re on your way.”) To make matters more complicated, Don, father of the brood, had a high profile position in the U.S. military, and rumors of family drama could have impacted his career.

Like my friend’s family, the Galvins dealt with the noise, the horror, the disruption by moving to the far edges of town, seeking geographical isolation so that neighborly complaints need not be an added worry.

Here’s the difficult part of writing about schizophrenia: readers want to find a grand discovery at the end; if not a cure, then a new and impressive treatment, or an historic advance in eliminating the problem. But solutions are elusive, and because of the stubborn nature of this disease, what may seem ground breaking to a researcher looks like a big, fat so-what to the average reader.

All told, Kolker has done a fine job describing what has taken place within the family and within the field; I thought he was a little hard on Mimi, who made a lot of errors but was facing a terrible dilemma during a period when our culture was very different from today. That aside, I do recommend this book to you. It will be available April 7, 2020.